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Recent Abstracts

Functional Assessment of Cancer Therapy: Fatigue (FACT-F)

Name of Questionnaire

Functional Assessment of Cancer Therapy: Fatigue (FACT-F)


A questionnaire assessing fatigue and anemia-related concerns in people with cancer.


Suzanne B. Yellen
David Cella

381 South Cottage Hill Avenue
Elmhurst, IL 60126
(+1) 877.828.3228



Cost & availability

License for use of any English version of a FACIT measure is granted free of charge. Investigators are required to complete one (1) collaborator's project information form for every project or study in which they plan on using one or more of the FACIT measures, and to notify us of any related reports or publications as they become available. Since scale construction and validation are developmental processes, we also appreciate a willingness on the part of the investigator(s) to share relevant components of their results to further reliability and validity testing (where applicable and appropriate).

License for use of a translated questionnaire may also require a fee. This decision is made on an individual project basis according to the nature of the trial, the questionnaires and translations to be used, the sponsor, and standing contractual arrangements. In general, there is a licensing fee for pharmaceutical and biotech companies to use the translated questionnaires in clinical trials of a commercial nature. For more information, please refer to the translation methods and services licensure link.


Patient self-administration
Interview administration

Time to complete

Not reported

Number of items

41 items

Domains & categories

5 domains

Name of categories/domains

Physical well-being (7 items)
Social/Family well-being (7 items)
Emotional well-being (6 items)
Functional well-being (7 items)
Fatigue (13 items)

Scaling of items

5-point Likert rating scale


To purchase manuals or scoring diskettes contact the staff at


The 41 items were found to be stable (test-retest r = 0.87) and internally consistent (coefficient alpha range = 0.95-0.96)
Symptom specific subscale showed good stability (test-retest r range = 0.84-0.90) and fatigue subscale showed strong internal consistency (coefficient alph range = 0.93-0.95).  Internal consistency of the miscellaneous nonfatigue items was lower but acceptable (alpha range = 0.59-0.70)

a. Test-Retest/Reproducibility: Reported 1
b. Internal Consistency: Reported 1


a. Convergent/Divergent: Reported 1

The FACT-F was validated against the Piper Fatigue Scale, POMS-V, POMS-F, MC-20 and the ECOG Performance Status Rating.

Fatigue subscale:  r = 0.66
Non-fatigue items: r = 0.79
POMS fatigue: r = -0.74
POMS vigor:  r = 0.66
Piper fatigue:  r = -0.75
Marlow-Crowne:  r = 0.04


Not reported

Minimally important difference

Not reported

Research use

Current implementation of the FACIT questionnaires range in use from Phase I, II, and III clinical trials.  

Clinical use

FACIT questionnaires are used in treatment evaluations, as an intervention tool in the clinical management of symptoms (both physical and psychological), and as an outcomes measure in health practice self studies.


45 translations are available.  Please see FACIT webiste for a complete list:


1.  Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E.
     Measuring fatigue and other anemia-related symptoms with the Functional Assessment of      
     Cancer Therapy (FACT) measurement system.  
     J Pain Symptom Manage. 1997 Feb;13(2):63-74.


Date of information

February 29, 2008

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