Functional Assessment of Cancer Therapy: Fatigue (FACT-F)

A questionnaire assessing fatigue and anemia-related concerns in people with cancer.

Developer

Address

E-mail

URL

Cost & availability

License for use of any English version of a FACIT measure is granted free of charge. Investigators are required to complete one (1) collaborator's project information form for every project or study in which they plan on using one or more of the FACIT measures, and to notify us of any related reports or publications as they become available. Since scale construction and validation are developmental processes, we also appreciate a willingness on the part of the investigator(s) to share relevant components of their results to further reliability and validity testing (where applicable and appropriate).

License for use of a translated questionnaire may also require a fee. This decision is made on an individual project basis according to the nature of the trial, the questionnaires and translations to be used, the sponsor, and standing contractual arrangements. In general, there is a licensing fee for pharmaceutical and biotech companies to use the translated questionnaires in clinical trials of a commercial nature. For more information, please refer to the translation methods and services licensure link.

Administration

Time to complete

Number of items

Domains & categories

Name of categories/domains

Physical well-being (7 items)
Social/Family well-being (7 items)
Emotional well-being (6 items)
Functional well-being (7 items)
Fatigue (13 items)

Scaling of items

Scoring

Reliability

The 41 items were found to be stable (test-retest r = 0.87) and internally consistent (coefficient alpha range = 0.95-0.96)
Symptom specific subscale showed good stability (test-retest r range = 0.84-0.90) and fatigue subscale showed strong internal consistency (coefficient alph range = 0.93-0.95). Internal consistency of the miscellaneous nonfatigue items was lower but acceptable (alpha range = 0.59-0.70)

Validity

The FACT-F was validated against the Piper Fatigue Scale, POMS-V, POMS-F, MC-20 and the ECOG Performance Status Rating.

Fatigue subscale: r = 0.66
Non-fatigue items: r = 0.79
POMS fatigue: r = -0.74
POMS vigor: r = 0.66
Piper fatigue: r = -0.75
Marlow-Crowne: r = 0.04

Responsiveness

Minimally important difference

Research use

Current implementation of the FACIT questionnaires range in use from Phase I, II, and III clinical trials.

Clinical use

Language

References

1. Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E.
    Measuring fatigue and other anemia-related symptoms with the Functional Assessment of
     Cancer Therapy (FACT) measurement system.
     J Pain Symptom Manage. 1997 Feb;13(2):63-74.