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Recent Abstracts

Functional Assessment of Cancer Therapy: General (FACT-G)

Name of Questionnaire

Functional Assessment of Cancer Therapy – General, Version 4 (FACT-G v. 4)


General quality of life instrument intended for use with a variety of chronic illness conditions. Originally validated in a general cancer population that included lung cancer patients. Core instrument in the Functional Assessment of Chronic Illness Therapy (FACIT) Measurement System, a system which has multiple disease-, treatment-, and condition-specific subscales to complement the FACT-G, including one for lung cancer ( FACT-L).


David Cella


David Cella, Ph.D.
Research Professor
Institute for Health Services Research and Policy Studies
Northwestern University Director
Center on Outcomes, Research and Education
Evanston Northwestern Healthcare
1000 Central Street
Suite 101
Evanston, IL USA 60201
FAX: 847-570-1735



Cost & availability

No charge for use of the English versions. Contact D Cella for permission.



Time to complete

5 minutes1

Number of items


Domains & categories


Name of categories/domains

Physical, social/family, emotional, and functional well-being.

Scaling of items

Five-point scale from 0 (not at all) to 4 (very much)


Subscale scores added to obtain total score. Alternative scoring includes the Trial Outcome Index (TOI), which is the sum of the Physical, Functional, and Lung Cancer Subscales. The TOI is reported to be an efficient and precise summary index of physical and functional outcomes.


a. Test-retest/reproducibility Reported1
b. Internal consistency Reported1


Discriminated between patients based on disease stage, performance status rating, and hospitalization status1. Differential responsiveness of subscales to groups that differed in physical, social, emotional, and functional well-being1. Compared as expected with Functional Living Index – Cancer (FLIC), Eastern Cooperative Oncology Group (ECOG) performance status rating, and shortened forms of the Profile of Mood States (POMS), Taylor Manifest Anxiety Scale (TMAS), and Marlowe-Crowne Social Desirability Scale (M-CSDS)1.



Minimally important difference

Not reported

Research use

Not reported in patients with lung cancer

Clinical use

Not reported in patients with lung cancer


FACT-G: Afrikaans, Bulgarian, Chinese (Mainland, Taiwan, Hong Kong), Czech, Danish, Dutch, English, Estonian, Finnish, French, Georgian, German, Greek, Hebrew, Hungarian, Italian, Japanese, Malay, Norwegian, Pedi, Polish, Portuguese, Russian, Slovak, Spanish, Swedish, Thai, Tswana, Turkish, Zulu


  1. Cella DF, Tulsky DS, Gray G, et al. The Functional Assessment of Cancer Therapy Scale: development and validation of the general measure. J Clin Oncol 1993; 11:570-79.

Date of information

May 1999

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