|
|
Quality of Life Questionnaire for Cancer Patients Treated with Anti-Cancer Drugs (QOL-ACD)
Name of Questionnaire
Quality of Life - Anti-Cancer Drugs (QOL-ACD)
Description
Quality of life measurement tool for patients undergoing
chemotherapy.
Developer
Minory Kurihara
Address
Department of Internal Medicine (Gastroenterology)
Toyosu Hospital
Showa University, 4-1-18
Toyosu, Koto-ku, Tokyo 135-8577
Japan
Tel: +81-3-35341151
Fax: +81-3-35319566
Administration
Self
Number of items
22
Domains & categories
4
Name of categories/domains
Daily Activities, Physical Condition, Social Activities, Mental
and Psychological Status
Scaling of items
Five-point scale from 5 ("best" or "good") to 1 ("worst" or
"bad") for 21 items. Five-point face scale for 1 item.
Scoring
Subscale scores are calculated as a simple sum of the items
within each subscale: Daily Activity (#1-6), Physical Condition
(#7-11), Psychological Condition (#12-16), Social Attitude
(#17-21), and Face Scale (#22). The total score is the sum of the
subscale scores.
Reliability
| a. Test-Retest / Reproducibility |
Reported: Spearman correlation coefficient was over 0.5 for 17
of the 22 items. The remaining 5 items had coefficients of 0.54,
0.45, 0.44, 0.43, and 0.28. Matsumoto reported intra-class
correlation coefficients to be at least moderately reliable except
item 6. Also, the item-domain correlation coefficients were greater
than 0.4 for all items except 10 and 16. They chose to exclude
items 6 and 16 because of low test-retest reliability and poor
convergent validity, respectively. This brought the range of
intra-class correlation coefficients to 0.610-0.866. |
| b. Internal Consistency |
Reported: Cronbach's alpha coefficient, Daily Activity r=0.821,
Physical Condition r=0.730, Psychological Condition r=0.582, Social
Attitude r=0.740. In the second study (Matsumoto, 2002) which
excluded 2 items, Cronbach's alpha coefficients ranged from 0.795
to 0.897. |
Validity
- Factor analysis provided strong support for the domain
structure. Factors = Functional, Psychosocial, Physical,
Mental.
- Inter-scale correlations were calculated, and the instrument
showed moderate correlations between subscales (range: 0.258 to
0.536). In the second study (Matsumoto, 2002), the coefficients
ranged from 0.612 to 0.866.
- Concurrent validity was measured against Performance Status
(PS), State-Trait Anxiety Inventory (STAI) and Self-Rating
Depression Scale (SDS). Performance Status correlated moderately
with Daily Activity and Physical Condition. State-Trait Anxiety
Inventory correlated moderately with all but Daily Activity.
Self-Rating Depression Scale correlated moderately with all of the
scales. The total score correlations showed r=0.551 for Performance
Status, r=0.554 for State-Trait Anxiety Inventory, and r=0.662 for
Self-Rating Depression Scale. In the Matsumoto study, Pearson's
correlation coefficients were calculated among the four domains and
for the relationship of each domain with the face scale. All
correlations among the four domains were below 0.70. Functional and
physical domains showed good correlation. Modest correlations were
found between the functional and mental domains (r=0.618), physical
and mental domains (r=0.588), and mental and psychosocial domains
(r=0.517). The face scale was most strongly correlated with the
mental domain.
- Clinical validity: statistically significant relationships
found between the functional domain and performance status, sex, or
weight loss; between the physical domain and performance status,
weight loss, albumin, or LDH; and between the psychosocial domain
and sex or age. These relationships were determined to be
clinically reasonable.
Research use
- Matsumoto T, Ohashi Y, Morita S, Kobayashi K, Shibuya M, Yamaji
Y, Eguchi K, Fukuoka M, Nagao K, Nishiwaki Y, Niitani H. The
quality of life questionnaire for cancer patients treated with
anticancer drugs (QOL-ACD): validity and reliability in Japanese
patients with advanced non-small-cell lung cancer. Quality of Life
Research. 2002 Aug;11(5):483-93.
Clinical use
Not reported.
Language
Japanese, English
References
- Kurihara M, Shimizu H,
Tsuboi K, Kobayashi K, Murakami M, Eguchi K, Shimozuma K.
Development of quality of life questionnaire in Japan: quality of
life assessment of cancer patients receiving chemotherapy.
Psycho-Oncology. 1999 Jul-Aug;8(4):355-63.
- Matsumoto T, Ohashi Y,
Morita S, Kobayashi K, Shibuya M, Yamaji Y, Eguchi K, Fukuoka M, K,
Nishiwaki Y, Niitani H. The quality of life questionnaire for
cancer patients treated with anticancer drugs (QOL-ACD): validity
and reliability in Japanese patients with advanced non-small-cell
lung cancer. Quality of Life Research. 2002
Aug;11(5):483-93.Nagao
Date of information
April 2003
|
