Name of Questionnaire
Quality of Life - Cancer Survivors (QOL-CS)
Quality of Life instrument designed to measure factors
concerning long-term cancer survivors.
Modeled after instruments developed at the City of Hope National
Medical Center (M. Grant, G. Padilla, and B. Ferrell), modified by
Betty R. Ferrell, PhD, RN, FAAN and Karen Hassey Dow, PhD, RN,
Betty R. Ferrell, PhD, RN, FAAN
City of Hope National Medical Center
Department of Nursing Research and Education
1500 East Duarte Road
Duarte, CA 91010
Tel: 626-301-8111 x 62825
Number of items
41 total (18 psychological, 8 physical, 8 social, 7
Domains & categories
Name of categories/domains
Psychological well-being, physical well-being, social
well-being, and spiritual well-being
Scaling of items
11-point scale from 0 (worst outcome) to 10 (best outcome)
Scores for each of the 41 items are averaged to obtain total
score. The average score for each of the subscales may also be
||Reported: Overall r=0.89, subscale scores: psychological
r=0.88, physical r=0.88, social r=0.81, spiritual r=0.90
|b. Internal Consistency
||Reported: Cronbach's alpha coefficient, Overall score r=0.93.
Subscale alpha scores: psychological r=0.89, physical r=0.77,
social r=0.81, spiritual r=0.71
- Content validity verified by literature
review, clinical experience, and an "initial pilot testing based on
a qualitative study using in-depth interviews with five long-term
cancer survivors". A panel of experts also reviewed the tool for
content and clarity.
- Predictive validity was measured using
step-wise multiple regression to determine factors most predictive
of overall quality of life among cancer survivors. 14 variables
accounted for 91% of the variance in overall QOL (primarily
control, aches and pain, uncertainty, satisfaction, future,
appearance and fatigue).
- Concurrent validity tested by Pearson's
correlation coefficient, compared to the Functional Assessment of
Cancer Therapy-General (FACT-G), with moderate to strong
correlations between associated subscales: QOL-CS physical to FACT
physical (r=0.74), QOL-CS psychological to FACT emotional (r=0.65),
QOL-CS social to FACT social (r=0.44), Overall r=0.78.
- Concurrent validity also tested by
Pearson's correlation coefficient applied to individual items of
- Construct validity measured by principal
components factor analysis.
- Construct validity measured by comparing
the known contrasting groups to determine if the QOL-CS
discriminates among groups based on disease stage, living
arrangements, gender, time since initial diagnosis, and
Minimally important difference
1. Sarna L, Padilla G, Holmes C, Tashkin D, Brecht ML,
Evangelista L. Quality of life of long-term survivors of
non-small-cell lung cancer. J Clin Oncol. 2002 Jul
English (no other languages reported)
- Ferrell BR, Hassey Dow K.
Quality of life among long-term cancer survivors. Oncology
(Huntingt). 1997 Apr;11(4):565-8, 571; discussion 572, 575-6.
- Ferrell BR, Hassey Dow K,
Grant M. Measurement of the quality of life in cancer survivors.
Quality of Life Research. 1995;4: 523-531.
- Ferrell BR, Hassey Dow K, Leigh S, Ly J,
Gulasekaram P. Quality of Life in Long-Term Cancer Survivors.
Oncology Nursing Forum. 1995 Nov; 22(6): 915-922.
Date of information