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Sickness Impact Profile

Name of Questionnaire

Sickness Impact Profile (SIP)


Generic measure used to evaluate the impact of disease on both physical and emotional functioning. Patients are asked to respond to the items as they are on that day. The measure has also been used in patients with COPD and asthma.


B Gilson & M Bergner, 1976 (revised 1981)

Copyright is held by Johns Hopkins University, 1977. All rights reserved. The Medical Outcomes Trust can provide information and permission for use.


Medical Outcomes Trust 

8 Park Plaza #503
Boston, MA 02116-4313
phone 617-426-4046, fax 617-426-4131



Cost & availability

Fee. Contact the Medical Outcomes Trust for information and permission to use.


Self, interview

Time to complete

20-30 minutes

Number of items


Domains & categories

2 overall domains (physical and psychosocial)

12 categories (sleep and rest, eating, work, home management, recreation and pastimes, ambulation, mobility, body care and movement, social interaction, alertness behavior, emotional behavior, communication)

Name of categories/domains

Physical: ambulation, mobility, body care and movement

Psychosocial: social interaction, communication, alertness behavior, emotional behavior; sleep and rest, eating, home management, recreation and pastimes, employment

An overall score can also be computed.

Scaling of items

Respondents check the items that apply to them (yes/no).


Overall score, 2 domain scores, and 12 category scores; items are weighted according to a standardized weighting scheme.


a. Test-retest/reproducibility Reported 1
b. Internal consistency Reported 1


Compared to clinical indices of asthma and disease-specific quality of life measures (AQLQ-Juniper 4 , 6 , SGRQ 2 , 3 , AQLQ-Marks 5 , symptoms & clinical efficacy 8 )


Reported 4 , 8 , 9

Minimally important difference

Not determined.

Research use

Reported, including clinical trial 4

Clinical use

Not reported.


Original: English

Translations: None currently authorized by the copyright holder. Guidelines for translation are available through the Medical Outcomes Trust or through Johns Hopkins University.


  1. Bergner M, Bobbitt RA, Carter WB, et al. The Sickness Impact Profile: development and final revision of a health status measure. Med Care 1981;19:787-805.
  2. Jones PW, Quirk FH, Baveystock CM. The St. George's Respiratory Questionnaire. Resp Med 1991;85(suppl):25-31.
  3. Jones PW, Quirk FH, Baveystock CM, Littlejohns P. A self-complete measure of health status for chronic airflow limitation. Am Rev Respir Dis 1992;145;1321-1327.
  4. Juniper EF, Guyatt GH, Ferrie PJ, Griffith LE. Measuring quality of life in asthma. Am Rev Respir Dis 1993;127:832-838.
  5. Marks GB, Dunn SM, Woolcock AJ. An evaluation of asthma quality of life questionnaire as a measure of change in adults with asthma. J Clin Epidemiol 1993;46:1103-1111.
  6. Rowe BH, Oxman AD. Performance of an asthma quality of life questionnaire in an outpatient setting. Am Rev Respir Dis 1993;148:675-681.
  7. Rutten-van Molken, van Doorslaer EKA, Jansen MCC, et al. Costs and effects of inhaled corticosteroids and bronchodilators in asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995;151: 975-82.
  8. Rutten-van Molken M, Custers F, Van Doorslaer E, Jansen C, Heurman L, Maesen F, Smeets J, Bommer A, Raaijmakers J. Comparison of performance of four instruments in evaluating the effects of salmeterol on asthma quality of life. Eur Respir J 1995;8:888-898.
  9. Jones PW, the Nedocromil Sodium Quality of Life Study Group. Quality of life, symptoms and pulmnary function in asthma: long-term treatment with nedocromil sodium examined in a controlled multicentre trial. Eur Respir J 1994;7:55-62.
  10. Bergner M, Bobbitt RA, Kressel S, et al. The Sickness Impact Profile: conceptual formulation and methodology for the development of a health status measure. Int J Health Serv 1976;6:393-415.
  11. Katz JN, Larson MG, Phillips CB, et al. Comparative measurement sensitivity of short and longer health status instruments. Med Care 1992;30:917-925.
  12. McSweeny AJ, Grant I, Heaton RK, Adams KM, Timms RM. Life quality of patients with chronic obstructive lung disease. Arch Intern Med 1982;142:473-478.
  13. Prigatano GP, Wright EC, Levin D. Quality of life and its predictors in patients with mild hypoxemia and chonric obstructive pulmonary disease. Arch Intern Med 1984;144:1613-1619.

Date of information

March 1999

Comments from developer/copyright holder

Yes (February 1999)

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